Dr. Eric Fombonne, director of the Montreal Children's Hospital (MCH) Autism Spectrum Disorders (ASD) Clinic, along with twelve other prestigious universities, is proud to embark on an ambitious project to investigate the genetic causes of ASD.

This project is unique for two primary reasons:

· The project comes at an exciting time in history. Recent scientific breakthroughs in genetics and neuroscience now make it possible to better understand the genetics of autism.

· It involves “simplex” families who have not been studied extensively. Simplex families have one child who has ASD, one or more children who do not have ASD, and two biological parents.

You and your family may want to participate in this important international research collaboration.

Participation in this project requires the completion of a number of questionnaires, interviews, and clinic visits, as well as the donation of DNA. Every member in your family will be asked to give a small amount of blood. Fragile-x and karyotype testing could be done at the same time. You will receive a comprehensive research evaluation, including psychology testing, as well as a report for your child once your family completes the study.

Your participation in this research is completely voluntary. Current and future services will not be altered if you do not participate in this study. You can also leave the study at any time without affecting the services that you normally receive.

If you believe that this research may interest you and your family, or if you would like further information, please contact the Project Coordinator, Cara Schwartz, at 514-412-4400 ext. 23325, or by email at cara.schwartz@muhc.mcgill.ca.